[HTML][HTML] Phosphodiesterase type 4D gene polymorphism: association with the response to short-acting bronchodilators in paediatric asthma patients

M Labuda, S Laberge, J Briere, D Bérubé… - Mediators of …, 2011 - hindawi.com
association of PDE4D genetic variations and response to asthma b2-agonists treatment in
Caucasian children… populations as frequency of tested polymorphisms and LD structure differ […

RGS5 gene and therapeutic response to short acting bronchodilators in paediatric asthma patients

M Labuda, S Laberge, J Brière, D Bérubé… - Pediatric …, 2013 - Wiley Online Library
… variant in phosphodiesterase 4D (PDE4D)13 gene, an enzyme … the relationship between
RGS5 gene polymorphisms and … the association of RGS5 genetic variations and response to β2-…

Therapeutic responses in asthma and COPD: bronchodilators

JF Donohue - Chest, 2004 - Elsevier
… The role of bronchodilators in relationship to the Dutch … selectively to different bronchodilators
such as short-acting β-… There was increasing acute bronchodilator response above plasma …

Pharmacogenetic approaches in the treatment of asthma

I Sayers, IP Hall - Current allergy and asthma reports, 2005 - Springer
… of 269 randomly selected children, the short-acting β-agonist … Phosphodiesterase 4D
enzymes are thought to be the critical … response to albuterol in children with and without a history …

ADRB2 gene polymorphism and emphysema heterogeneity can modulate bronchodilator response in patients with emphysema

M Nojiri, S Mizuno, K Nishiki, R Kato… - Pulmonary …, 2018 - Elsevier
… ) gene has been thought to have an important role in the differential response to β 2 -agonist
therapy for asthma… However, previous studies have shown little evidence for an association

The rs2601796 variant in ADCY9 gene is associated with severe asthma and less bronchodilator response

HMP Teixeira, ÁA Cruz, TS Jesus, MBR de Santana… - Gene, 2023 - Elsevier
… Severe asthma patients require treatment with high dose of inhaled … Short-acting
bronchodilators were withheld 6 h prior to … Genetic polymorphisms of the beta-2 andrenergic …

Meta-analysis: effect of long-acting β-agonists on severe asthma exacerbations and asthma-related deaths

SR Salpeter, NS Buckley, TM Ormiston… - Annals of internal …, 2006 - acpjournals.org
… All trials allowed the use of as-needed short-acting β-… β-agonists produce bronchodilation
and improve asthma symptoms, … Short-term use in acute asthma exacerbations improves peak …

Pharmacogenetics of respiratory disease

IP Hall, SB Liggett - Pharmacogenetics, 2016 - api.taylorfrancis.com
… In this study, the acute bronchodilator response in 121 … the clinical response to repetitive
administration of short-acting … The phosphodiesterase (PDE) 4D subfamily is thought to be the …

[PDF][PDF] Respiratory medicine–genetic base for allergy and asthma

A Binia, M Kabesch - Swiss medical weekly, 2012 - smw.ch
… suggested to be associated with childhood asthma, even though … (ICS), long and short
acting β2-adrenoreceptor agonists (… with Gly16Gly showed a better response to albuterol [70]. It …

Phosphodiesterase 4B inhibition: a potential novel strategy for treating pulmonary fibrosis

M Kolb, B Crestani, TM Maher - European Respiratory Review, 2023 - Eur Respiratory Soc
… sclerosis (SSc)-associated ILD and other chronic fibrosing … stroke [30] and response to
short-acting bronchodilators [31]. … -induced late-asthmatic response and reduced biomarkers of …